Pancuronium bromide ( NSC 293162 )

Catalog No. M12200 CAS No. 15500-66-0

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Product Name

Pancuronium bromide
Note

Research use only, not for human use.
Brief Description

Pancuronium dibromide is a competitive AChR antagonist (IC50 = 5.5 nM) and acts as a skeletal muscle relaxant.
Description

Pancuronium dibromide is a competitive AChR antagonist (IC50 = 5.5 nM) and acts as a skeletal muscle relaxant. Pancuronium dibromide interrupts neuromuscular transmission by competing with acetylcholine for receptor sites on the motor end-plate.
Synonyms

NSC 293162
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

AChR; mAChR
Research Area

Neurological Disease
Indication

——

CAS Number

15500-66-0
Formula Weight

732.67
Molecular Formula

C35H60Br2N2O4
Purity

>98%(HPLC)
Solubility

Very soluble in water
SMILES

CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1[N+]4(CCCCC4)C)C)CC[C@]5([C@H]3C[C@@H]([C@@H]5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-]
Chemical Name

——

1.Stovner J, et al. Br J Anaesth. 1975 Sep;47(9):949-54.

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